100th Anniversary of Macromolecular Science Viewpoint: Biological Stimuli-Sensitive Polymer Prodrugs and Nanoparticles for Tumor-Specific Drug Delivery
نویسندگان
چکیده
منابع مشابه
Development of pH Sensitive Nanoparticles for Intestinal Drug Delivery Using Chemically Modified Guar Gum Co-Polymer
The aim of the research work was to chemically modify guar gum(GG) as a pH sensitive co-polymer and formulating intestinal targeting ESO nanoparticles (NPs) using the synthesized co-polymer. Poly acrylamide-grafted-guar gum (PAAm-g-GG) co-polymer was synthesized by free radical polymerization. Chemical modification of PAAm-g-GG by alkaline hydrolysis results in formation of a pH-sensitive co-po...
متن کاملDevelopment of pH Sensitive Nanoparticles for Intestinal Drug Delivery Using Chemically Modified Guar Gum Co-Polymer
The aim of the research work was to chemically modify guar gum(GG) as a pH sensitive co-polymer and formulating intestinal targeting ESO nanoparticles (NPs) using the synthesized co-polymer. Poly acrylamide-grafted-guar gum (PAAm-g-GG) co-polymer was synthesized by free radical polymerization. Chemical modification of PAAm-g-GG by alkaline hydrolysis results in formation of a pH-sensitive co-po...
متن کاملdevelopment of ph sensitive nanoparticles for intestinal drug delivery using chemically modified guar gum co-polymer
the aim of the research work was to chemically modify guar gum(gg) as a ph sensitive co-polymer and formulating intestinal targeting eso nanoparticles (nps) using the synthesized co-polymer. poly acrylamide-grafted-guar gum (paam-g-gg) co-polymer was synthesized by free radical polymerization. chemical modification of paam-g-gg by alkaline hydrolysis results in formation of a ph-sensitive co-po...
متن کاملPolymer Nanoparticles for Smart Drug Delivery
In the recent decades, polymers are widely used as biomaterials due to their favorable properties such as good biocompatibility, easy design and preparation, a variety of structures and interesting bio-mimetic character. Especially in the field of smart drug delivery, polymer played a significant role because it can deliver therapeutic agents directly into the intended site of action, with supe...
متن کاملProtein-polymer hybrid nanoparticles for drug delivery.
Amphiphilic bovine serum albumin-poly(methyl methacrylate) conjugate forms nanoparticles with the uniform size of ~100 nm by self-assembling. Loaded with the hydrophobic anti-tumor drug camptothecin, the nanoparticle efficiently delivers drugs into cancer cells, and thus inhibits ~79% of tumor growth in animals compared with free drug.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Macro Letters
سال: 2020
ISSN: 2161-1653,2161-1653
DOI: 10.1021/acsmacrolett.0c00488